Genome-guided CRISPR intelligence

Search, design, train, and evaluate CRISPR guides in one AI/ML-powered workspace.

Explore genome targets, generate candidate spacers, assess multiplex guide compatibility, and train or use reusable genome-specific ML models from your account workspace.

Guest accessYou may run one analysis at a time. Create an account to save results, train private genome models, and run whole-genome targetability statistics.

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Candidate guide design

Generate and screen candidate spacers

Design

Species model Cas system PAM pattern

Target type Preferred region

TargetEnter a gene, identifier, genomic interval, or DNA sequence.

Advanced design settings

Return top candidates Candidates to screen Minimum GC Maximum GC Off-target mismatches Off-target scope Candidate discovery always stays within the specified interval. Model partitions limit Model version

Analysis output

Results

✂No analysis yet

Choose a mode and submit an analysis to view results.

Search, design, train, and evaluate CRISPR guides in one AI/ML-powered workspace.

Generate and screen candidate spacers

Evaluate guides individually and as a panel

Results

Targetability profile

Target alignment map

Search, design, train, and evaluate CRISPR guides in one AI/ML-powered workspace.

Find exact and nearby guide matches

Generate and screen candidate spacers

Evaluate guides individually and as a panel

Results

Targetability profile

Target alignment map